分子細胞生理学研究室

最近の論文発表

2020

Sugimoto-Ishige, A., Harada, M., Tanaka, M., Terooatae, T., Adachi, Y., Takahashi, Y., Tanaka, T., Burroes, PD., Hikida, M., and Takemori, T.
Bim establishes the B cell repertoire from early to late in the immune response. Int. Immunol. in press.

Kondo, N., Hikida, M., Nakada, M., Sakurai, Y., Hirata, E., Takeno, S., and Suzuki, M.
Glioma Stem-like cells can be targeted in boron neutron capture therapy with boronophenylalanine. Cancers (Basel) 12(10):3040

Hong, R., Lai, N., Xiong, E., Ouchida, R., Sun, J., Zhou, Y., Hikida, M., Tsubata, T., Tagawa, M., Wang, Y., and Wang, JY.
Distinct roles of BCNP1 in B cell development and activation. Int. Immunol. 32(1)17-26.

2019

Matsuo, T., Hashimoto, M., Sakaguchi, S., Sakaguchi, N., Ito, Y., Hikida, M., Tsuruyama, T., Sakai, K., Yokoi, H., Shirakashi, M., Tanaka, M., Ito, H., Yoshifuji, H., Ohmura, K., Fujii, T., and Mimori, T.
Strain-specific manifestation of lupus-like systemic autoimmunity caused by Zap70 mutation. J. Immunol. 202(11)3161-3172.

Hong, R., Lai, N., Ouchida, R., Xiong, E., Zhou, Y., Min, Q., Liu, J., Tang, Y., Hikida, M., Tsubata, T., Wang, Y., Wang, JY.
The B cell novel protein 1 (BCNP1) regulates BCR signaling and B cell apoptosis. Eur. J. Immunol. 49(6)911-917.

2017

Kiso, K., Yoshifuji, H., Oku, T., Hikida, M., Kitagori, K., Hirayama, Y., Nakajima, T., Haga, H., Tsuruyama, T., and Miyagawa-Hayashino, A.
Transgelin-2 is upregulated on activated B cells and expressed in hyperplastic follicles in lupus erythematosus patients. PLoS One 12(9)e0184738.

2016

Kim, B., Takeuchi, A., Hikida, M., and Matsuoka, S.
Roles of the mitochodrial Na⁺-Ca²⁺ exchanger, NCLX, in B lymphocyte chemotaxis. Sci. Rep. 6 28378.

2015

Todo, K., Koga, O., Nishikawa, M., and Hikida, M.
Modulation of Igβ is essential for the B cell selection in germinal center.Sci Rep.5, 10303-10317.

2014

Shiheido, H., Aoyama, T., Takahashi, H., Hanaoka, K., Abe, T., Nishida, E., Chen, C., Koga, O., Hikida, M., Shibagaki, Y., Morita, A., Nikawa, T., Hattori, S., Watanabe, T., and Shimizu, J.
Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLCγ1 following T-cell stimulation. Eur J Immunol.44(6)1770-1780.

Shiheido, H., Kitagori, K., Sasaki, C., Kobayashi, S., Aoyama, T., Urata, K., Oku, T., Hirayama, Y., Yoshitomi, H., Hikida, M., Yoshifuji, H., Mimori, T., Watanabe, T., and Shimizu, J.
Human T cells expressing BEND3 on their surface represent a novel subpopulation that preferentially produces IL-6 and IL-8. Immun Inflamm Dis.2(1)35-43.

Todo, K., Koga, O., Nishikawa, M., and Hikida, M.
IgG1 cytoplasmic tail is essential for cell surface expression in Igβ down-regulated cells. Biochem Biophys Res Commun.445(3)572-577.

Lorès, P., Vernet, N., Kurosaki, T., Van de Putte, T., Huylebroeck, D., Hikida, M., Gacon, G., and Touré, A.
Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse. Dev Biol.386(2)419-427.

Shiheido, H., Chen, C., Hikida, M., Watanabe, T., and Shimizu, J.
Modulation of the human T cell response by a novel non-mitogenic anti-CD3 antibody. PLoS One.9(4)e94324-e94333.

2013

Capietto, A-H., Kim, S., Sanford, D., Linehan, D., Hikida, M., Kurosaki, T., and Novack, D.
Down regulation of PLCγ2/β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer. J Exp Med.210(11)2257-2271.